Breast cancer metastases prognosis

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Skip to Content. Use the menu to see other pages. The symptoms and signs that people with metastatic breast cancer may experience depend on where and how much the cancer has spread.

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Metastasis is a complex process in which malignant cancer cells from the breast spread into other regions of the body. Once metastasis has occurred, it is much more difficult to effectively treat breast cancer. Sometimes metastasis has occurred at the time the original breast cancer is diagnosed.

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From tometastatic disease developed in of the patients treated for breast cancer at the University of Maryland Medical System. In general, patients with initially negative axillary nodes had a longer median time until relapse development of metastatic disease and a longer survival time after diagnosis of metastases than patients with initially positive nodes. Liver was the least common initial metastatic site; while liver metastasis was seen only in patients with positive axillary nodes, it carried the worst prognosis.

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Stage 4 breast cancer refers to cancer that has spread beyond the breast tissue into other areas of the body. To understand the prognosis for stage 4 breast cancer, it helps to know something about the process of metastasis. In the case of breast cancer, receiving a stage 4 diagnosis may mean the cancer has reached organs outside of the breasts, such as your bones, lungs, liver, or even your brain.

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Metastatic breast cancer also called stage IV or advanced breast cancer is not a specific type of breast cancer. It's the most advanced stage of breast cancer. Metastatic breast cancer is breast cancer that has spread beyond the breast and nearby lymph nodes to other organs in the body most often the bones, lungs, liver or brain.

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We aimed to determine the prognostic impact of time between primary breast cancer and diagnosis of distant metastasis metastatic-free interval, MFI on the survival of metastatic breast cancer patients. Consecutive patients diagnosed with metastatic breast cancer in — in eight hospitals in the Southeast of the Netherlands were included and categorised based on MFI. Survival curves were estimated using the Kaplan—Meier method.

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Metastatic breast canceralso referred to as metastasesadvanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer where the breast cancer cells have spread to distant sites beyond the axillary lymph nodes. There is no cure for metastatic breast cancer; it often can be effectively treated. There is no stage after IV.

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Common sites include distant organs like the lung, liver, bone and brain. Even after an original tumor is removed, microscopic tumor cells may remain in the body, which allows the cancer to return and spread. Patients may initially be diagnosed with metastatic diseaseor they may develop metastases months or years after their initial treatment. The risk of breast cancer returning and metastasizing varies from person to person and depends greatly on the biology of the tumor and the stage at the time of the original diagnosis.

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Most women with stage IV breast cancer are mainly treated with systemic therapy. This may include hormone therapy, chemotherapy, targeted therapy, or some combination of these. Local treatments such as surgery or radiation might also be used to help prevent or treat symptoms.

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Metastatic breast cancer is breast cancer that has spread beyond the breast to other organs in the body, most often the bones, lungs, liver or, less commonly, brain. There are many words used, but they actually mean the same thing. When referring to a specific area or site of metastatic breast cancer, the term secondary is often used — for example a secondary in the bone.

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