The Centre for Adverse Reactions Monitoring CARM continues to receive reports of sexual dysfunction associated with the use of antidepressants and antipsychotics. Sincethe most frequently reported medicines have been fluoxetine 17 reportscitalopram 12paroxetine 7venlafaxine 5risperidone 12 and clozapine 7. Most often this takes the form of lack of libido.
The following are some of the side effects that are known to be associated with olanzapine. Just because a side effect is stated here doesn't mean that all people taking olanzapine will experience it. You should read the patient information leaflet that is supplied with your medication for more information about side effects associated with olanzapine.
Sexual dysfunction is a common condition in patients taking antipsychotics, and is the most bothersome symptom and adverse drug effect, resulting in a negative effect on treatment compliance. It is known that hyperprolactinemia is a major cause of sexual dysfunction. Based on the blockade of dopamine D2 receptors, haloperidol, risperidone, and amisulpride are classed as prolactin-elevating antipsychotics, while olanzapine, clozapine, quetiapine, ziprasidone, and aripiprazole are classed as prolactin-sparing drugs.
All FDA black box warnings are at the end of this fact sheet. Please review before taking this medication. Olanzapine is a medication that works in the brain to treat schizophrenia.
With the advent of newer antipsychotic drugs, side effects such as sexual dysfunction have been a major contributor toward treatment compliance. There are only a few studies that have compared different atypical antipsychotic agents regarding sexual dysfunction. We have not come across any data in this area on Indian population.
Zyprexa is a medication known as an atypical antipsychotic that is used to treat symptoms of schizophrenia. The drug is also sometimes prescribed to treat symptoms of bipolar disorder. Are there any major differences between Zyprexa and other antipsychotics used to treat Zyprexa?
It has a pleotrophic pharmacology and affects dopaminergic, serotonergic, muscarinic and adrenergic activities. Clinical studies and trials suggest olanzapine is superior to haloperidol and also maybe superior to risperidone in terms of efficacy and side-effect profiles. The therapeutic advantage of recent antipsychotics so-called atypical antipsychotics has been attributed to alpha-2 adrenergic antagonist effects Nutt,